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Galectin Therapeutics glycopolymers
Glycopolymers, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glycopolymers/glycopolymers+by+raft+polymerization/pm40372066-105-1-24
Average 90 stars, based on 1 article reviews
glycopolymers - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Migration:

Article Title: Synthetic Glycopolymers in Tumor Immunotherapy.
Article Snippet: Glycopolymers, as an emerging immunomodulatory material, exhibit considerable promise in the field of tumor immunotherapy.. Compared to native saccharides, they offer significant advantages, including enhanced immune activity, controllable structure and sequence, elevated stability, and high purity.. By mimicking the multivalency of native sugar chains, glycopolymers significantly enhance their interactions with receptors, a phenomenon known as the “glycocluster effect.” Glycopolymers are capable of modulating immune cell functions, inhibiting tumor immune evasion, and reconfiguring the tumor microenvironment.

Expressing:

Article Title: Synthetic Glycopolymers in Tumor Immunotherapy.
Article Snippet: Glycopolymers, as an emerging immunomodulatory material, exhibit considerable promise in the field of tumor immunotherapy.. Compared to native saccharides, they offer significant advantages, including enhanced immune activity, controllable structure and sequence, elevated stability, and high purity.. By mimicking the multivalency of native sugar chains, glycopolymers significantly enhance their interactions with receptors, a phenomenon known as the “glycocluster effect.” Glycopolymers are capable of modulating immune cell functions, inhibiting tumor immune evasion, and reconfiguring the tumor microenvironment.

Binding Assay:

Article Title: Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method
Article Snippet: .. Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 30 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table of Contents Graphic for Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 31 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 ..

Synthesized:

Article Title: Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method
Article Snippet: .. Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 30 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table of Contents Graphic for Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 31 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 ..

Conjugation Assay:

Article Title: Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method
Article Snippet: .. Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 30 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Table of Contents Graphic for Selective and Tunable Galectin Binding of Glycopolymers Synthesized by a Generalizable Conjugation Method Can Zhou,1 Heidi L. Reesink2 and David Putnam*,1,3 Page 31 of 31 ACS Paragon Plus Environment Biomacromolecules 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 ..



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Proposed cellular uptake, intracellular trafficking, and autophagy behaviors of DOX-loaded glycopolymer nanomicelles in Human Glioblastoma Carcinoma cells

Journal: Journal of Materials Science. Materials in Medicine

Article Title: Glycopolymer nanomicelles: pH-responsive drug delivery, endocytosis pathway, autophagy behavior, and the effect of autophagy inhibitors

doi: 10.1007/s10856-024-06837-4

Figure Lengend Snippet: Proposed cellular uptake, intracellular trafficking, and autophagy behaviors of DOX-loaded glycopolymer nanomicelles in Human Glioblastoma Carcinoma cells

Article Snippet: Taken together, this work provided a preliminary understanding of the intracellular drug delivery properties of glycopolymer micelles and demonstrated the effect of different autophagy inhibitors, which may benefit the innovation of “autophagy regulator-combined nanotherapeutics” towards high performance tumor chemotherapy.

Techniques:

Top: Preparation of DOX-loaded glycopolymer micelles with pH-responsive manners; Bottom: ( A ) DLS characterization of the hydrodynamic particle size and distributions of the blank and DOX-loaded micelles (inset: TEM image of the DOX-loaded micelles, scale bar: 200 nm); ( B ) time- dependent colloidal stability of the DOX-loaded micelles in PBS buffer (pH 7.4, 10 mM) at 37 °C

Journal: Journal of Materials Science. Materials in Medicine

Article Title: Glycopolymer nanomicelles: pH-responsive drug delivery, endocytosis pathway, autophagy behavior, and the effect of autophagy inhibitors

doi: 10.1007/s10856-024-06837-4

Figure Lengend Snippet: Top: Preparation of DOX-loaded glycopolymer micelles with pH-responsive manners; Bottom: ( A ) DLS characterization of the hydrodynamic particle size and distributions of the blank and DOX-loaded micelles (inset: TEM image of the DOX-loaded micelles, scale bar: 200 nm); ( B ) time- dependent colloidal stability of the DOX-loaded micelles in PBS buffer (pH 7.4, 10 mM) at 37 °C

Article Snippet: Taken together, this work provided a preliminary understanding of the intracellular drug delivery properties of glycopolymer micelles and demonstrated the effect of different autophagy inhibitors, which may benefit the innovation of “autophagy regulator-combined nanotherapeutics” towards high performance tumor chemotherapy.

Techniques: